• CreBuilder®

    Creatine is a conditionally essential nutrient, whose synthesis requires three amino acids (arginine, glycine and methionine) and three organs (kidney, liver and muscle). In the kidney, arginine transfers its amidino group to glycine to synthesize GAA.


    CreBuilder® is the latest rumen-protected guanidinoacetic acid (PR-GAA) developed by Beijing Gendone Biotechnology Co., Ltd. CreBuilder® is a nutritional feed additive, which belongs to "amino acid, amino acid salt and its analogues". CreBuilder® adopts a microcapsule multilayer coating process, which is an ideal creatine source for high-yield ruminants. CreBuilder® supplies more metabolizable guanidinoacetic acid than unprotected products. CreBuilder® is used in ruminant feed to ensure adequate supply of creatine, improve energy efficiency, promote protein deposition, improve performance, slaughter performance, and meat quality, and relieve production stress. 







    Creatine is a conditionally essential nutrient, whose synthesis requires three amino acids (arginine, glycine and methionine) and three organs (kidney, liver and muscle). In the kidney, arginine transfers its amidino group to glycine to synthesize GAA. Therefore, guanidinoacetic acid is the direct endogenous precursor of creatine in the organism. GAA is transferred to the liver, where S-adenosylmethionine (SAM) gives its methyl group to GAA to synthesize creatine. Creatine is then transported by the bloodstream to the target cells with high energy need, such as skeletal muscle, mammary gland, heart, brain, sperm and immune cells. Creatine plays a key role in energy transfer and supply via creatine-phosphocreatine system. Deitary supplemental CreBuilder®  can increase creatine levels in the body by 20%.





     Guanidinoacetic acid content ≥75%

     More than 90% GAA can be protected and can't be destroyed in rumen, thus to absorb in small intestine

     The product is used microcapsule multilayer coating process, resistant to granulation













    For beef cattle & sheep

    Improve energy efficiency, increase weight gain by 10%;
    Promote muscle growth, reduce fat deposition & significantly improved body shape;
    Increase the slaughter and net meat rate by 1-3%, and improve meat quality;
    Relieve heat stress, transportation stress;

    Replace monensin and clenbuterol.



    For cow & milk goat

    Improve energy efficiency, milk production and quality;
    Improve feed efficiency and reduce nitrogen emissions;
    Enhance physical fitness and reduce postpartum metabolic diseases;
    Relieve production stress, such as heat stress;
    Improve reproductive performance.












    This product can be added to premixes, concentrates, concentrate supplements or fully mixed rations, and is resistant to abrasion and high temperature.






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